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CK-MB
Overview
CK-MB (creatine kinase-MB) is an isoenzyme of the enzyme creatine kinase, predominantly found in heart muscle cells. It plays a crucial role in the energy metabolism of cardiac tissues. When heart muscle cells are damaged, such as in a myocardial infarction (heart attack), CK-MB is released into the bloodstream. Measuring CK-MB levels in the blood is useful for diagnosing and assessing the extent of heart damage. Elevated CK-MB levels typically indicate myocardial injury, and the enzyme’s levels rise within a few hours after the onset of chest pain, peak around 24 hours, and return to normal within 48-72 hours. This time course helps in the diagnosis and monitoring of acute coronary events.
Frequently Asked Questions
CK-MB stands for creatine kinase-MB, an isoenzyme found primarily in heart muscle cells.
CK-MB plays a critical role in the energy metabolism of cardiac muscle cells by facilitating the conversion of creatine to phosphocreatine, which is essential for energy storage and release.
CK-MB levels are measured to help diagnose myocardial infarctions (heart attacks) and assess the extent of heart muscle damage.
A CK-MB test is performed using a blood sample drawn from a vein in the arm.
Elevated CK-MB levels should be discussed with a healthcare provider to determine the underlying cause and appropriate treatment. Further diagnostic tests and clinical evaluation will be necessary to establish a definitive diagnosis and treatment plan.
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