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CA 125, also known as cancer antigen 125, is a protein found in the coelomic epithelium which covers the body cavity. It rises in the blood in cases of ovarian cancer, as well as in some other cancers and certain benign conditions.
The CA 125 serum test determines the amount of CA 125 protein in the bloodstream. This protein can be located on the outer layer of certain ovarian cancer cells. The blood’s concentration can assist in the diagnosis and monitoring of ovarian cancer.
The CA-125 Serum Test is primarily done to monitor certain types of cancer, particularly ovarian cancer. It measures the level of CA-125, a protein that can be elevated in the blood of individuals with ovarian cancer or other conditions such as endometriosis or pelvic inflammatory disease.
The CA-125 Serum Test measures the level of CA-125, a protein biomarker, in the blood. Elevated CA-125 levels can indicate various conditions, including ovarian cancer, though it is not specific to this disease and can also be elevated in other conditions such as endometriosis or pelvic inflammatory disease.
If CA-125 Serum results are present (elevated), it may indicate various conditions, including ovarian cancer, though elevated levels can also occur in other conditions such as endometriosis or pelvic inflammatory disease. Further evaluation, including imaging studies and possibly tissue biopsies, may be necessary to determine the underlying cause.
If CA-125 Serum results are absent (within normal range), it suggests that CA-125 levels are not elevated. However, it does not rule out the possibility of ovarian cancer or other conditions, as not all cases of ovarian cancer result in elevated CA-125 levels. Additional diagnostic tests and evaluations may be needed, especially if there are other concerning symptoms or clinical findings.
The CA-125 serum test is typically recommended for individuals with symptoms suggestive of ovarian cancer, those with a family history of ovarian cancer, or individuals at high risk due to certain genetic mutations or other risk factors.
The CA-125 serum test is generally safe, but minor risks include discomfort during blood collection, bruising, fainting, and, rarely, infection or bleeding at the puncture site. However, these risks are minimal.
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