Adenosine Deaminase (ADA) - Ascitic Fluid

The ADA (Adenosine Deaminase) test measures the level of adenosine deaminase enzyme activity in ascitic fluid. This test is primarily used to aid in the diagnosis of tuberculous peritonitis, a form of tuberculosis that affects the peritoneum (the membrane lining the abdominal cavity). Elevated ADA levels in ascitic fluid can indicate the presence of tuberculous peritonitis, helping healthcare providers in making accurate diagnoses and initiating appropriate treatment.

The ADA (Adenosine Deaminase) test on ascitic fluid is performed to aid in the diagnosis of tuberculous peritonitis, a form of tuberculosis affecting the peritoneum (the membrane lining the abdominal cavity). Elevated levels of ADA in ascitic fluid can indicate the presence of tuberculous peritonitis, helping healthcare providers in making accurate diagnoses and initiating appropriate treatment. This test is particularly useful in regions where tuberculosis is prevalent or in individuals with risk factors for tuberculosis infection.

The ADA (Adenosine Deaminase) test on ascitic fluid is typically recommended when tuberculous peritonitis is suspected as a potential cause of ascites (abnormal accumulation of fluid in the abdominal cavity). It's especially relevant in regions where tuberculosis is prevalent or in individuals with risk factors for tuberculosis infection. Healthcare providers may consider this test for patients presenting with symptoms suggestive of peritoneal tuberculosis, such as abdominal pain, distension, weight loss, fever, and night sweats, particularly if other causes of ascites have been ruled out or if there are concurrent findings suggestive of tuberculosis elsewhere in the body.

High chloride levels (hyperchloremia) may suggest dehydration, kidney problems, respiratory alkalosis, or metabolic acidosis. Low chloride levels (hypochloremia) can indicate conditions such as fluid loss, certain kidney diseases, metabolic alkalosis, or congestive heart failure.

During the ADA (Adenosine Deaminase) test on ascitic fluid, a sample of ascitic fluid is collected from the patient. This is typically done through a procedure called paracentesis, where a healthcare provider inserts a needle or catheter into the abdominal cavity to withdraw fluid.

Once the ascitic fluid sample is obtained, it is sent to a laboratory for analysis. In the lab, the level of ADA enzyme activity in the ascitic fluid sample is measured. The test results are then reported to the healthcare provider, who interprets them in the context of the patient's clinical presentation and other diagnostic findings to aid in the diagnosis of tuberculous peritonitis.